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Stem Cell Research News
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 Researchers
Tout Need For All Forms Of Stem Cell Research
In light of a recent breakthrough study in adult stem cell
research published in Nature, a group of the world's
leading researchers, the International Society for Stem Cell
Research (ISSCR), cautions against discounting the potential
benefits of all forms of stem cell research, adult and embryonic
alike. |
05
Sept 2008 |
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Interstate
Rivalry Put On Hold By Stem Cell Research
Victoria and New South Wales have put aside their competitive
interstate rivalry to collaborate on a stem cell research
project, as announced by Innovation Minister Gavin Jennings and
NSW Minister for Science and Medical Research, Verity Firth. |
05
Sept 2008 |
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Human
Stem Cell Methods Featured In CSH Protocols
The use of human embryonic stem cells is opening new avenues for
research, from the understanding of normal human development to
the treatment of a wide variety of diseases. This month's issue
of Cold Spring Harbor Protocols (
Myocardial
Regeneration By Intracoronary Infusion Of Selected Population Of
Stem Cells In Acute Myocardial Infarction Randomized Multicenter
Trial
REGENT is the second-largest trial using bone marrow-derived
cells in patients with acute MI and the first large trial for
head-to-head comparison of selected and unselected cells
Intracoronary infusion of unselected and selected bone marrow
cells proved to be safe and feasible Treatment with
intracoronary infusion of bone marrow cells did not lead to
significant improvement of LVEF and LV volumes in comparison to
control group, however there was a trend towards significant
improvement of LVEF in patients with severely depressed baseline
LVEF receiving either MNC or CD34+CXCR4+ bone marrow cells
REGENT is a multicenter, randomized trial for comparison of
intracoronary infusion of bone marrow-derived unselected
mononuclear cells (MNC) and selected CD34+CXCR4+ cells in 200
patients with acute myocardial infarction and reduced LVEF ≤
40%. |
03
Sept 2008 |
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New
Stem Cell Tools To Aid Drug Development
Scientists have designed, developed and tested new molecular
tools for stem cell research to direct the formation of certain
tissue types for use in drug development programmes.A
collaborative team of scientists from Durham University and the
North East England Stem Cell Institute (NESCI) have developed
two synthetic molecules which can be used to coax stem cells to
'differentiate' - that is, transform into other forms of tissue. |
03
Sept 2008 |
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Researchers
Devise Means To Create Blood By Identifying Earliest Stem Cells
Johns Hopkins researchers have discovered the earliest form of
human blood stem cells and deciphered the mechanism by which
these embryonic stem cells replicate and grow. They also found a
surprising biological marker that pinpoints these stem cells,
which serve as the progenitors for red blood cells and
lymphocytes. |
30
Aug 2008 |
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Scientists
Change Living Pancreatic Cells Into Insulin Producers
US scientists have discovered a way to transform living
pancreatic cells in mice into another type of cell that produces
insulin without having to revert to the stem cell stage,
creating what is now a third route for cell reprogramming to add
to the existing methods of iPS (induced pluripotent stem cells)
and hES (human embryonic stem cells). |
28
Aug 2008 |
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Michigan
Board Approves Stem Cell Measure For November Ballot
The Michigan Board of State Canvassers on Thursday certified a
ballot measure that would loosen Michigan's restrictions on
human embryonic stem cell research, the <a href="http://www.freep.%3c/td%3e%3ctd%20width="
" align=right valign=top>26 Aug 2008 |
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Wisdom
Teeth As Source Of Stem Cells
Researchers in Japan have successfully made stem cells from
wisdom teeth, creating an alternative source of pluripotent
cells for researching and treating disease and avoiding the
ethical problems surrounding the use of embryonic stem cells. |
22
Aug 2008 |
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Researchers
Report New Process Of Creating Red Blood Cells From Embryonic
Stem Cell
A team of researchers at
Advanced Cell Technology, the
University of Illinois-Chicago and the
Translational Stem Cell Research Conference The New York
Stem Cell Foundation's Third Annual Translational Stem Cell
Research Conference will be held at the Rockefeller University,
New York City.Co-chaired by:Paul Nurse, PhD and Douglas Melton,
PhDTuesday, October 14Road to the Clinic: From Lab to
Therapy, panel 1:30pmResearch Highlights for a Lay Audience,
panel 4:00pmThird Annual Gala Dinner, 6:30 pm Learn moreWednesday,
October 15Translational Stem Cell Research Conference,
starting at 9:00amConfirmed Speakers Include: Ed Baetge,
PhD; Mickie Bhatia, PhD; Ali Brivanlou, PhD; Pete Coffey, PhD;
George Daley, MD, PhD; Kevin Eggan, PhD; Gerald Fischbach, MD;
John Gearhart, PhD; Robin Goland, MD; Harry Heimberg, MD, PhD;
Chris Henderson, PhD; Konrad Hochedlinger, PhD; Insoo Hyun, PhD;
Hans Keirstead, PhD; Jeffrey Kordower, PhD; Thane Kreiner, PhD;
Ihor Lemischka, PhD; John McNeish; Douglas A. |
22
Aug 2008 |
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Cell
Transplants Protect Intestinal Tissue From Autoimmune Attack In
Animal Model
Massachusetts General Hospital (MGH) investigators have found
that infusions of a particular bone marrow stem cell appeared to
protect gastrointestinal tissue from autoimmune attack in a
mouse model. |
22
Aug 2008 |
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Clinical-Scale
Generation Of Functional Red Blood Cells From Human Embryonic
Stem Cells
Advanced Cell Technology, Inc. ("ACT") (OTC: ACTC.PK) reported
that it is feasible to differentiate and mature human embryonic
stem cells (hESCs) into functional oxygen-carrying red blood
cells (RBCs) under conditions suitable for scale-up. |
21
Aug 2008 |
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Allogeneic,
"Off-The-Shelf", Stem Cells Are Safe And Effective For Cervical
Spine Fusion
Australian regenerative medicine company Mesoblast Limited (ASX:MSB)(PINK:MBLTY),
announced that its allogeneic, or "off-the-shelf", cell therapy
product was safe and highly effective in preclinical trials for
interbody fusion of the cervical spine in the neck. |
21
Aug 2008 |
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STEMCELL
Technologies Introduces AggreWell™400 For Standardized Embryonic
Stem Cell And Induced Pluripotent Stem Cell Research
STEMCELL Technologies, a leader in specialty cell culture media,
cell separation products and ancillary reagents for stem cell
research, today announced the release of the AggreWell™400
plates, a revolutionary tool for researchers using embryonic and
induced pluripotent stem cells (ESC and iPSC). |
21
Aug 2008 |
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70
Doctoral Fellowships Funded By NSF To Move Stem Cell Discoveries
From Bench To Bedside
Rutgers University has received a $3.2 million grant from the
National Science Foundation (NSF) to apply engineering, physical
science and mathematical disciplines to stem cell research. In
funding 70 doctoral fellowships, the program can equip experts
in fields such as cell and molecular biology, computational
modeling and biomaterials to move stem-cell breakthroughs from
the biology lab into practical and commercially viable
therapies. |
21
Aug 2008 |
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UCSF
Faculty Receive $13.7M From CIRM For Stem Cell Research
Five UCSF stem cell scientists have received New Faculty grants
from the California Institute for Regenerative Medicine, support
that will allow them to pursue lines of investigation ultimately
aimed at developing treatment strategies for such conditions as
cancer, heart disease, tooth regeneration, liver disease and
amyotrophic lateral sclerosis. |
21
Aug 2008 |
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Stem
Cell Therapies May Be Right Under Our Nose - Vision.org
In criticizing mega-church pastor Rick Warren's recent televised
conversation with Presidential candidates Senators Barak Obama
and John McCain, those opposed to the event argued that the
fundamental barrier that separates church and state had been
violated. |
21
Aug 2008 |
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Stem
Cell Indicator For Bowel Cancer Should Lead To Better Survival
Rates
Stem cell scientists have developed a more accurate way of
identifying aggressive forms of bowel cancer, which should
eventually lead to better treatment and survival rates. Bowel
cancer is the third most common cancer in the UK. |
21
Aug 2008 |
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CMV
Disease In Stem Cell Transplantation: Prevention And Drug
Resistance
Cytomegalovirus (CMV) is a significant cause of morbidity and
mortality in recipients of hematopoietic stem cell
transplantation. The clinical manifestations of CMV disease are
serious and range from gastrointestinal disease to
life-threatening pneumonia, myelosuppression, retinitis, and
encephalitis. |
15
Aug 2008 |
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StemCells,
Inc. To Present On Batten Disease To The California Institute Of
Regenerative Medicine's Oversight Committee
StemCells, Inc. (NASDAQ:STEM) announced that it has accepted an
invitation by the California Institute of Regenerative Medicine
(CIRM) to present on Batten Disease at the upcoming meeting of
CIRM's Independent Citizens Oversight Committee (ICOC). |
11
Aug 2008 |
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BIO
Welcomes Advances In Stem Cell Research
BIO President and CEO Jim Greenwood issued the following
statement regarding the news that researchers at the Harvard
Stem Cell Institute created 20 disease-specific stem cell lines
thru the new induced pluripotent stem cell (iPS) technique: "The
creation of stem cells lines carrying the genes or genetic
components of ten diseases is a great step forward in the quest
to understand, treat and eventually cure disease. |
11
Aug 2008 |
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Daley
And Colleagues Create 20 Disease-Specific Stem Cell Lines -
Lines To Be Part Of New HSCI IPS Collection Available To
Researchers
Harvard Stem Cell Institute researcher George Q. Daley, MD, PhD,
also associate director of the Stem Cell Program at Children's
Hospital Boston, and HSCI colleagues Konrad Hochedlinger and
Chad Cowan have produced a robust new collection of
disease-specific stem cell lines, all of which were developed
using the new induced pluripotent stem cell (iPS) technique. |
08
Aug 2008 |
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Daley
And Colleagues Create 20 Disease-Specific Stem Cell Lines -
Lines To Be Part Of New HSCI IPS Collection Available To
Researchers
Harvard Stem Cell Institute researcher George Q. Daley, MD, PhD,
also associate director of the Stem Cell Program at Children's
Hospital Boston, and HSCI colleagues Konrad Hochedlinger and
Chad Cowan have produced a robust new collection of
disease-specific stem cell lines, all of which were developed
using the new induced pluripotent stem cell (iPS) technique. |
08
Aug 2008 |
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Scientists
Replicate Diseases In The Lab With New Stem Cell Lines
A set of new stem cell lines will make it possible for
researchers to explore ten different genetic disorders-including
muscular dystrophy, juvenile diabetes, and Parkinson's
disease-in a variety of cell and tissue types as they develop in
laboratory cultures. |
08
Aug 2008 |
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Putting
MicroRNAs On The Stem Cell Map
Embryonic stem cells are always facing a choice-either to
self-renew or begin morphing into another type of cell
altogether. It's a tricky choice, governed by complex gene
regulatory circuitry driven by a handful of key regulators known
as "master transcription factors," proteins that switch gene
expression on or off. |
08
Aug 2008 |
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Scientists
Create Disease-Specific Stem Cell Lines
US researchers have found a way to produce immortal cell strains
and tissue types from diseased patients by converting their
cells into pluripotent stem cells with the same genetic errors.
The new cell lines will enable scientists to investigate ten
different genetic disorders like Parkinson's, muscular
dystrophy, and type 1 diabetes in the test tube instead of in
the patient, a huge step forward compared to current methods. |
07
Aug 2008 |
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NIH
Grants Will Fund University Of Wisconsin Stem Cell Research
The
National Institute of General Medical Sciences recently
awarded an $8.9 million grant to a team of researchers from the
University of Wisconsin-Madison to investigate the "fundamental
power" of human embryonic stem cells, as well as cells that have
been "reprogrammed" to function like embryonic stem cells, the
Recipe
For Cell Reprogramming Adds Protein - Embryonic-Like Stem Cells
Can Be Created Without Cancer-Causing Gene
A drug-like molecule called Wnt can be substituted for the
cancer gene c-Myc, one of four genes added to adult cells to
reprogram them to an embryonic-stem-cell-like state, according
to Whitehead researchers. |
07
Aug 2008 |
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New
Insights Into The Development Of Epithelial Cells - MDC
Researchers Discover More Diversity Than Expected
Epithelial cells cover all internal and external surfaces of the
body. They have an upper and a lower side, which have different
functions. Until now, scientists assumed that these two poles
develop in all epithelial cells in the same manner -
irrespective of whether they are located in the heart, in the
retina, or in the nervous system. |
07
Aug 2008 |
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ALS
Stem Cell Breakthrough
Scientists in the US have converted skin cells from an
82-year-old woman with amyotrophic lateral sclerosis (ALS) into
stem cells that formed motor neurons with the same genetic make
up as the patient. |
01
Aug 2008 |
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Thermo
Fisher Scientific Significantly Broadens Stem Cell Offering
Thermo Fisher Scientific Inc., the world leader in serving
science, has expanded its Thermo Scientific Stem Cell
ExcellenceTM program, providing new tools and technologies to
advance the stem cell research process. |
01
Aug 2008 |
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Neurons
Created From Skin Cells Of Elderly ALS Patients
Less than 27 months after announcing that he had institutional
permission to attempt the creation of patient and
disease-specific stem cell lines, Harvard Stem Cell Institute (HSCI)
Principal Faculty member Kevin Eggan proclaimed the effort a
success - though politically imposed restrictions and scientific
advances prompted him to use a different technique than
originally planned. |
01
Aug 2008 |
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New
And Potentially Better Source Of Platelets For Transfusion
Clot-forming blood cells, or platelets, can drop to dangerously
low levels in diseases such as anemia and in patients undergoing
chemotherapy. To replace these critical cells, doctors filter
platelets from donated blood, but this approach can increase the
risk of transmitting blood infections and cause other side
effects in patients who need frequent transfusions. |
29
July 2008 |
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Adult
Stem Cells Activated In Mammalian Brain
Adult stem cells originate in a different part of the brain than
is commonly believed, and with proper stimulation they can
produce new brain cells to replace those lost to disease or
injury, a study by UC Irvine scientists has shown. |
25
July 2008 |
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News
From Weill Cornell Medical College June/July 2008
New Cancer Stem Cell Identified - A Potential Metastatic
Disease Target?Researchers from Weill Cornell Medical
College have identified a type of cancer stem cell that might
initiate metastatic cancer, which spreads beyond the original,
primary tumor site and to other locations within the body. |
18
July 2008 |
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Standards
In Stem Cell Research
Standards in stem cell research help both scientists and
regulators to manage uncertainty and the unknown, according to
new research funded by the Economic and Social Research Council.
Efforts to standardise practices across different labs is,
however, a balancing act where the autonomy of scientists and
fragility of living material need to be weighed against the need
for comparable data. |
18
July 2008 |
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California
Institute For Regenerative Medicine To Fund Stem Cell Research
At Cedars-Sinai Heart Institute
The California Institute for Regenerative Medicine (CIRM) has
awarded a planning grant to the Cedars-Sinai Heart Institute to
support its researchers in their study of regenerative stem
cell-based approaches to heart attacks, congestive heart failure
and pacing abnormalities. |
18
July 2008 |
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Mesoblast
Limited Is Granted Key Stem Cell Patent In The United States
Australia's regenerative medicine company, Mesoblast Limited (ASX:MSB)(PINK:MBLTY),
today announced that the United States Patent and Trade Mark
Office (USPTO) has granted a key patent, US Patent 7,399,632,
through to at least the year 2019. |
16
July 2008 |
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Stem
Cells Heal Chronic Inflammation In The Gut - May Help Restore
Immune System To Normal Function For Crohn's Disease
Stem cells are being studied at NewYork-Presbyterian/Weill
Cornell to heal the gut in subjects suffering from Crohn's
disease. Physician-scientists believe that these cells might
help to restore the ability of the immune system to control
inflammation by secreting anti-inflammatory proteins into the
digestive tract, allowing for regeneration of tissue and
prevention of scar tissue. |
16
July 2008 |
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New
Cancer Stem Cell Identified - A Potential Metastatic Disease
Target?
Researchers from Weill Cornell Medical College have identified a
type of cancer stem cell that might initiate metastatic cancer,
which spreads beyond the original, primary tumor site and to
other locations within the body. |
16
July 2008 |
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Stem
Cell Researchers At UM Enrolling Patients In Heart Failure Study
- Catheter Injection System To Be Used
Stem cell researchers at the University of Miami Miller School
of Medicine are ready to enroll patients in another breakthrough
study aimed at treating heart failure. They have received
approval from the Food and Drug Administration for a study using
a Helical Infusion catheter system to inject stem cells into the
heart. |
16
July 2008 |
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Researchers
And Representatives Gain Insight Into Stem Cell Research Funding
Opportunities In Maryland
To provide researchers and companies with insight into stem cell
research funding opportunities and an overview of the
application process for stem cell research in Maryland, the
Maryland Stem Cell Research Commission (Commission) recently
hosted two informational sessions at the Montgomery County
campus of Johns Hopkins University (JHU) and the Greenspring
campus of the Kennedy Krieger Institute. |
16
July 2008 |
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Stem
Cell Treatment For Children With Eye Nerve Disease Called
'Medical Hoax'
Two pediatric eye surgeons at Washington University School of
Medicine in St. Louis expressed alarm over what they label a
"21st century snake oil" scam.Recent newspaper stories including
several from Missouri -- have reported parents flying their
children to main land China for umbilical cord stem cell (CSC)
infusions. |
12
July 2008 |
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Another
Step Forward For Muscle Stem Cells
Research by Dr Amy Wagers and her team at Harvard University,
USA, has shown promise for the use of muscle stem cell as a
therapy for conditions such as muscular dystrophy. The
researchers successfully transplanted muscle stem cells from
healthy mice into the muscles of mice that show symptoms similar
to Duchenne muscular dystrophy. |
12
July 2008 |
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Identification
Of Genes That Control Embryonic Stem Cell Fate
Scientists have identified about two dozen genes that control
embryonic stem cell fate. The genes may either prod or restrain
stem cells from drifting into a kind of limbo, they suspect. The
limbo lies between the embryonic stage and fully differentiated,
or specialized, cells, such as bone, muscle or fat. |
13
July 2008 |
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Gene
Directs Stem Cells To Build The Heart
Researchers have shown that they can put mouse embryonic stem
cells to work building the heart, potentially moving medical
science a significant step closer to a new generation of heart
disease treatments that use human stem cells. |
03
July 2008 |
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New
Technique Produces Genetically Identical Stem Cells
Adult cells of mice created from genetically reprogrammed cells
- so-called induced pluripotent stem (IPS) stem cells - can be
triggered via drug to enter an embryonic-stem-cell-like state,
without the need for further genetic alteration. |
02
July 2008 |
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Potential
Role Of Stem Cells In The Treatment Of Incontinence And Pelvic
Prolapse
ORLANDO, FL (UroToday.com) - The potential role of stem cells in
the treatment of incontinence and pelvic prolapse has been a
subject of much attention. A group from Torrance, CA reported on
their promising experience using muscle derived stem cells (MDSC)
grown on scaffolds of small intestinal submucosal (SIS) to
stimulate repair of the vaginal wall in rats (Abstract #1369). |
02
July 2008 |
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